产品货号：
Z37445
中文名称：
Hu P glycoprotein/ABCB1 Purified抗体
英文名称：
Anti-Hu P glycoprotein/ABCB1 Purified Antibody (Clone#UIC2)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Hu P glycoprotein/ABCB1 Purified Antibody (Clone#UIC2) |
| 指标别名 | ABCB1;CD243;GP170;MDR1;Multidrug resistance protein 1;P glycoprotein;P glycoprotein 1;P-gp |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | FCM,IP,IHC,IHC-F |
| 基因名称 | ABCB1 |
| 克隆号 | UIC2 |
| 抗体来源 | Mouse |
| 免疫原 | NIH 3T3 cells transfected with human CD243 (MDR-1) cDNA.The mouse monoclonal antibody UIC2 recognizes an extracellular epitope on CD243 (MDR-1),an approximately 170kDa ABC transporter expressed on hematopoietic stem cells,B,T,and NK cells,or on many multidrug resistant cancer cells.This antibody preferentially recognizes CD243 in the process of transporting substrate. |
| 计算分子量 | 141kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | CD243,also known as multidrug resistant protein 1 (MDR-1) or P-glycoprotein (Pgp) is an ATP binding cassette (ABC)-containing efflux transporter for xenobiotic lipophilic compounds with broad substrate specificity.It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs.This protein also functions as a transporter in the blood-brain barrier.It is expressed in many tissues,including the brain,liver,pancreas,testes,kidney,and blood (B,T,NK cells,but not monocytes). |
| Uniprot ID | P08183 |
| 基因名全称 | ATP binding cassette subfamily B member 1 |
| 蛋白名全称 | Multidrug resistance protein 1 |
| 推荐稀释比 | Immunohistochemistry (paraffin sections):Heat mediated antigen retrieval in citrate buffer pH6. Flow cytometry:1～4μg/mL |
相关搜索：Hu P glycoprotein/ABCB1 Purified抗体，Hu P glycoprotein抗体，ABCB1 Purified单抗